Internalizing Symptoms and Adverse Childhood Experiences Associated With Functional Connectivity in a Middle Childhood Sample.

ABSTRACT:

Background

Research has found overlapping associations in adults of resting-state functional connectivity (RSFC) to both internalizing disorders (e.g., depression, anxiety) and a history of traumatic events. The present study aimed to extend this previous research to a younger sample by examining RSFC associations with both internalizing symptoms and adverse childhood experiences (ACEs) in middle childhood.

Methods

We used generalized linear mixed models to examine associations between a priori within- and between-network RSFC with child-reported internalizing symptoms and ACEs using the Adolescent Brain Cognitive Development dataset (N = 10,168, mean age = 9.95 years, SD = 0.627).

Results

We found that internalizing symptoms and ACEs were associated with both multipl

SUBMITTER: Albertina EA 

PROVIDER: S-EPMC9596616 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature