Postoperative anion gap associates with short- and long-term mortality after cardiac surgery: A large-scale cohort study.

ABSTRACT:

Objective

To investigate whether postoperative anion gap (AG) is associated with short- and long-term mortality in patients following cardiac surgery.

Materials and methods

We conducted a retrospective cohort study of adults who underwent cardiac surgery from the Medical Information Mart for Intensive Care - III database. The generalized additive model (GAM), logistic regression, and Cox regression were performed to assess the correlations between AG levels and in-hospital, 90-day, and 4-year mortality. Linear regression was used to evaluate the associations between AG and length of stay (LOS).

Results

Totally, 6,410 subjects were enrolled in this study and classified into tertiles based on the initial AG levels. The GAM indicated a positive association between initia

SUBMITTER: Li J 

PROVIDER: S-EPMC9596785 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature