Benign thyroid disease and the risk of breast cancer: An updated systematic review and meta-analysis.

ABSTRACT:

Background

The correlation between benign thyroid disease (BTD) and breast cancer (BC) has long been discussed. However, the definite relationship and potential mechanism between them are still disputed. The current meta-analysis aimed at performing a comprehensive assessment of the relationship between different types of benign thyroid disease and the risk of breast cancer, furthermore, assessing whether benign thyroid disease exerts an influence on the aggressiveness of breast cancer.

Method

A systematic literature search (PubMed, Web of Science, MEDLINE, and Embase databases) identified studies to evaluate the correlation between BTD and BC risk. Data were analyzed using version 16.0 STATA software, including the odds ratio (OR) and its corresponding 95% confidence interv

SUBMITTER: Han M 

PROVIDER: S-EPMC9596990 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature