Systematic Review on Efficacy of Preventive Measures for Surgical Site Infection by Multiple-Drug Resistant Gram-Negative Bacilli.

ABSTRACT:

Background

There are no specific recommendations for prevention of surgical site infection (SSI) caused by multidrug resistant Gram-negative bacilli (MDR-GNB). Our objective was to systematically review the literature evaluating the efficacy and safety of measures specifically designed to prevent MDR-GNB SSI.

Methods

We searched MEDLINE, EMBASE, CINAHL and LILACS databases up to February 18, 2020. Randomized trials and observational cohort studies evaluating the efficacy of preventive measures against MDR-GNB SSI in adult surgical patients were eligible. We evaluated methodological quality of studies and general quality of evidence using Newcastle-Ottawa scale, Cochrane ROBINS-I and GRADE method. Random-effects meta-analyses were performed using Review Manager V.5.3 software

SUBMITTER: Matos JA 

PROVIDER: S-EPMC9597116 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature