Impact of nationwide hepatocellular carcinoma surveillance on the prognosis in patients with chronic liver disease.

ABSTRACT:

Background/aims

This study aimed to investigate the effect of hepatocellular carcinoma (HCC) surveillance using the Korea National Liver Cancer Screening Program on the receipt of curative treatment for HCC and mortality in patients with chronic liver disease.

Methods

This population-based cohort study from the Korean National Health Insurance Service included 2003 to 2015 claims data collected from 1,209,825 patients aged ≥40 years with chronic hepatitis B, chronic hepatitis C, and liver cirrhosis. Patients were divided according to HCC surveillance using ultrasonography and serum alpha-fetoprotein every 6-12 months. The study outcomes were the receipt of curative treatment (surgical resection, radiofrequency ablation, or liver transplantation) and all-cause mortality.

R

SUBMITTER: Sohn W 

PROVIDER: S-EPMC9597220 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature