Global prevalence of depression and anxiety in patients with hepatocellular carcinoma: Systematic review and meta-analysis.

ABSTRACT:

Background/aims

Depression and anxiety are associated with poorer outcomes in patients with hepatocellular carcinoma (HCC). However, the prevalence of depression and anxiety in HCC are unclear. We aimed to establish the prevalence of depression and anxiety in patients with HCC.

Methods

MEDLINE and Embase were searched and original articles reporting prevalence of anxiety or depression in patients with HCC were included. A generalized linear mixed model with Clopper-Pearson intervals was used to obtain the pooled prevalence of depression and anxiety in patients with HCC. Risk factors were analyzed via a fractional-logistic regression model.

Results

Seventeen articles involving 64,247 patients with HCC were included. The pooled prevalence of depression and anxiety in pa

SUBMITTER: Tan DJH 

PROVIDER: S-EPMC9597225 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature