3D-printed bioactive ceramic scaffolds with MoSe₂ nanocrystals as photothermal agents for bone tumor therapy.

ABSTRACT: Large scale bone defects after bone tumor resection are difficult to reconstruct and repair, and there is also the possibility of tumor recurrence. Photothermal therapy (PTT) has the function of inhibiting tumor cells, but the risk of damage to normal cells is the main factor limiting the clinical application of PTT drugs, and most of them have a weak effect on regeneration for bone defects. Therefore, specific biomaterials that simultaneously eliminate bone tumors, have low toxicity, and promote osteogenesis have attracted considerable attention. In this paper, we successfully fabricated bioactive bredigite scaffolds (MS-BRT) functionalized with MoSe₂ nanocrystals using a combination of 3D printing and hydrothermal methods. MS-BRT scaffolds not only have low toxicity and good o

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9597292 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature