Targeted detection and molecular epidemiology of turkey coronavirus spike gene variants in turkeys and chickens.

ABSTRACT: Turkey coronavirus (TCoV) is a member of the Avian coronavirus species with infectious bronchitis virus (IBV), which is considered to be the source of TCoV. These 2 viruses are highly similar in all regions of their genomes, except for the spike gene, which is necessary for virus attachment. Although TCoV causes severe enteric disease in turkey poults, it does not cause clinical disease in chickens. However, considering that TCoV can infect chickens, it is important to distinguish TCoV from IBV in chickens. This is particularly true for chickens that are housed near turkeys and thus might be infected with TCoV and serve as a silent source of TCoV for turkeys. We developed and validated a real-time PCR assay to detect the spike gene of TCoV and sequenced a portion of this gene to eva

SUBMITTER: Wilkes RP 

PROVIDER: S-EPMC9597335 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature