Metabolic reprogramming enables the auxiliary diagnosis of breast cancer by automated breast volume scanner.

ABSTRACT: Breast cancer is the leading cause of female cancer-related deaths worldwide. New technologies with enhanced sensitivity and specificity for early diagnosis and monitoring of postoperative recurrence are in critical demand. Automatic breast full volume scanning system (ABVS) is an emerging technology used as an alternative imaging method for breast cancer screening. Despite its improved detection rate of malignant tumors, ABVS cannot accurately stage breast cancer preoperatively in 30-40% of cases. As a major hallmark of breast cancer, the characteristic metabolic reprogramming may provide potential biomarkers as an auxiliary method for ABVS.

Objective

The objective of this study was to identify differential metabolomic signatures between benign and malignant breast tumors and among

SUBMITTER: Liu J 

PROVIDER: S-EPMC9597368 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature