Estimates of SARS-CoV-2 Omicron BA.2 Subvariant Severity in New England.

ABSTRACT:

Importance

The SARS-CoV-2 Omicron subvariant, BA.2, may be less severe than previous variants; however, confounding factors make interpreting the intrinsic severity challenging.

Objective

To compare the adjusted risks of mortality, hospitalization, intensive care unit admission, and invasive ventilation between the BA.2 subvariant and the Omicron and Delta variants, after accounting for multiple confounders.

Design, setting, and participants

This was a retrospective cohort study that applied an entropy balancing approach. Patients in a multicenter inpatient and outpatient system in New England with COVID-19 between March 3, 2020, and June 20, 2022, were identified.

Exposures

Cases were assigned as being exposed to the Delta (B.1.617.2) variant, the Omicron (B.1

SUBMITTER: Strasser ZH 

PROVIDER: S-EPMC9597387 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature