Impact of HIV-1 subtypes on gross deletion in the nef gene after Korean Red Ginseng treatment.

ABSTRACT:

Background

The number of primary human immunodeficiency virus (HIV)-1 non-B subtype infections (non-B) and that of reports regarding the differences in the pathogenesis of subtype B and non-B infections are increasing. However, to the best of our knowledge, there have been no reports on gross deletion in the nef gene (gΔnef) in non-B infections.

Methods

To determine whether there is a difference in the change in CD4⁺ T cells after treatment with Korean Red Ginseng (KRG) between patients with subtype B and non-B infections, we retrospectively analyzed and compared the annual decrease in CD4⁺ T cells (AD) and the proportion of gΔnef in 77 patients who were followed for more than 10 years in the absence of combination antiretroviral th

SUBMITTER: Cho YK 

PROVIDER: S-EPMC9597433 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature