Limited permissibility of ENL-R and Mv-1-Lu mink cell lines to SARS-CoV-2.

ABSTRACT: The SARS-CoV-2 pandemic started in the end of 2019 in Wuhan, China, which highlighted the scenario of frequent cross-species transmission events. From the outbreak possibly initiated by viral spill-over into humans from an animal reservoir, now we face the human host moving globally while interacting with domesticated and peridomestic animals. The emergence of a new virus into the ecosystem leads to selecting forces and species-specific adaptations. The adaptation of SARS-CoV-2 to other animals represents a risk to controlling the dissemination of this coronavirus and the emergence of new variants. Since 2020, several mink farms in Europe and the United States have had SARS-CoV-2 outbreaks with human-mink and mink-human transmission, where the mink-selected variants possibly hold evolution

SUBMITTER: Le Bideau M 

PROVIDER: S-EPMC9597503 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature