Postoperative radiotherapy might be a risk factor for second primary lung cancer: A population-based study.

ABSTRACT:

Background

Surgery is the main curative therapeutic strategy for patients with initial primary lung cancer (IPLC). Most international guidelines recommend regular follow-ups after discharge to monitor patients for tumor recurrence and metastasis. As the overall survival (OS) in patients with lung cancer improves, their risk of secondary primary lung cancer (SPLC) increases. Previous studies on such patients lack separate assessment of different survival outcomes and evaluation of high-risk factors for SPLC. Therefore, we aimed to determine the correlation between high-risk factors and causes of death in patients with SPLC, based on the Surveillance, Epidemiology, and End Results (SEER) database.

Methods

We screened the SEER database for patients with IPLC and SPLC from 2004

SUBMITTER: Mo Y 

PROVIDER: S-EPMC9597700 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature