Detection of a New Emerging Strain of Rabbit Haemorrhagic Disease Virus 2 (GI.2) in China.

ABSTRACT:

Introduction

In May 2020, an outbreak of rabbit haemorrhagic disease 2 (RHD2) caused by the rabbit haemorrhagic disease virus 2 (RHDV2, GI.2) occurred in Sichuan, China. The acute onset and short disease course resulted in rabbit mortality as high as 42.86%. Currently, basic research on the aetiology and genetic characteristics of GI.2 is lacking in China.

Material and methods

Pathological changes in various tissues from infected rabbits were investigated and the viral genome was characterised. This study used RT-PCR, histopathology and scanning electron microscopy to identify the pathogen in samples from infected rabbits that had died. Phylogenetic trees were constructed based on whole genome sequence analysis, and recombination events were analysed.

Results

RT-PCR i

SUBMITTER: Chen W 

PROVIDER: S-EPMC9597937 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature