Optimization of Phlorizin Extraction from Annurca Apple Tree Leaves Using Response Surface Methodology.

ABSTRACT: Phlorizin is a plant-derived molecule with relevant anti-diabetic activity, making this compound a potential functional component in nutraceutical formulations for the management of glycemia. It is noteworthy that promising sources for the extraction of phlorizin include apple tree leaves, a by-product of apple fruit production. The main aim of this study was to optimize the extraction process of phlorizin from Annurca apple tree leaves (AALs) using response surface methodology (RSM), and to determine the potential nutraceutical application of the obtained extract. The results of the RSM analysis indicate a maximum phlorizin yield of 126.89 ± 7.579 (mg/g DW) obtained under the following optimized conditions: MeOH/H₂O, 80:20 + 1% HCOOH as the extraction solvent; 37.7 °C as the ex

SUBMITTER: Maisto M 

PROVIDER: S-EPMC9598179 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature