The Role of Long Noncoding RNAs on Male Infertility: A Systematic Review and In Silico Analysis.

ABSTRACT: Male infertility is a complex disorder affecting many couples worldwide. Long noncoding RNAs (lncRNAs) regulate important cellular processes; however, a comprehensive understanding of their role in male infertility is limited. This systematic review investigates the differential expressions of lncRNAs in male infertility or variations in lncRNA regions associated with it. The PRISMA guidelines were used to search Pubmed and Web of Science (1 June 2022). Inclusion criteria were human participants, patients diagnosed with male infertility, and English language speakers. We also performed an in silico analysis investigating lncRNAs that are reported in many subtypes of male infertility. A total of 625 articles were found, and after the screening and eligibility stages, 20 studies were include

SUBMITTER: Kyrgiafini MA 

PROVIDER: S-EPMC9598197 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature