Novel Insights into Fungal Infections Prophylaxis and Treatment in Pediatric Patients with Cancer.

ABSTRACT: Invasive fungal diseases (IFDs) are a relevant cause of morbidity and mortality in children with cancer. Their correct prevention and management impact patients' outcomes. The aim of this review is to highlight the rationale and novel insights into antifungal prophylaxis and treatment in pediatric patients with oncological and hematological diseases. The literature analysis showed that IFDs represent a minority of cases in comparison to bacterial and viral infections, but their impact might be far more serious, especially when prolonged antifungal therapy or invasive surgical treatments are required to eradicate colonization. A personalized approach is recommended since pediatric patients with cancer often present with different complications and require tailored therapy. Moreover, while t

SUBMITTER: Bossu G 

PROVIDER: S-EPMC9598217 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature