Genomic Diversity of NDM-Producing <i>Klebsiella</i> Species from Brazil, 2013-2022.

ABSTRACT: Background: Since its first report in the country in 2013, NDM-producing Enterobacterales have been identified in all the Brazilian administrative regions. In this study, we characterized by antimicrobial susceptibility testing and by molecular typing a large collection of NDM-producing Klebsiella isolates from different hospitals in Brazil, mainly from the state of Sao Paulo, over the last decade. Methods: Bacterial isolates positive for bla_NDM-genes were identified by MALDI-TOF MS and submitted to antimicrobial susceptibility testing by disk diffusion or broth microdilution (for polymyxin B). All isolates were submitted to pulsed-field gel electrophoresis, and isolates belonging to different clusters were submitted to whole genome sequencing by Illu

SUBMITTER: Camargo CH 

PROVIDER: S-EPMC9598336 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature