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A Novel ssDNA Aptamer Targeting Carcinoembryonic Antigen: Selection and Characterization.


ABSTRACT: One of the major causes of a drastically shorter life expectancy and one of the most prevalent diseases in the world today is cancer. Given the data on the rise in cancer cases throughout the world, it is obvious that, despite the diagnostic techniques currently being used, there is a pressing need to develop precise and sensitive techniques for early diagnosis of the disease. A high degree of affinity and specificity towards particular targets is maintained by the short nucleic acid molecules known as aptamers. Aptamers outperform antibodies due to their unique benefits, such as their simplicity in synthesis and modification, lack of toxicity, and long-term stability. Utilizing an accurate recognition element and a robust signal transduction mechanism, molecular diagnostics can be extreme

SUBMITTER: Yunussova N 

PROVIDER: S-EPMC9598387 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature