Periodontal changes following distraction osteogenesis in patients with cleft lip and palate: a clinical trial.

ABSTRACT:

Objectives

To evaluate inflammatory mediator levels and periodontal changes following distraction osteogenesis (DO) in patients with cleft lip and palate (CLP) using mid-maxillary distraction (MMD).

Materials and methods

A total of 20 healthy patients with CLP with Class III malocclusion were included. Segmental forward advancement of the anterior maxilla from the second premolars on both sides using DO was performed. A custom-made, tooth-borne distractor connecting buccal molar segments to the anterior maxilla was used for 7 days with 0.5-mm distraction for the first 2 days and then increased to 1 mm daily until overcorrection. Crevicular interleukin IL-1β and tumor necrosis factor TNF-α levels were measured during distraction. Periodontal clinical parameters and indices we

SUBMITTER: Moussa H 

PROVIDER: S-EPMC9598851 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature