Dataset Information

Ligand-Promoted Surface Solubilization of TiO₂ Nanoparticles by the Enterobactin Siderophore in Biological Medium.

ABSTRACT: Titanium dioxide nanoparticles (TiO₂-NPs) are increasingly used in consumer products for their particular properties. Even though TiO₂ is considered chemically stable and insoluble, studying their behavior in biological environments is of great importance to figure their potential dissolution and transformation. The interaction between TiO₂-NPs with different sizes and crystallographic forms (anatase and rutile) and the strong chelating enterobactin (ent) siderophore was investigated to look at a possible dissolution. For the first time, direct evidence of anatase TiO₂-NP surface dissolution or solubilization (i.e., the removal of Ti atoms located at the surface) in a biological medium by this siderophore was shown and the progressive formation of a hexacoordinated titanium-enterobactin (Ti-ent) complex observed. This complex was characterized by UV-visible and Fourier transform infrared (FTIR) spectroscopy (both supported by Density Functional Theory calculations) as well as electrospray ionization mass spectrometry (ESI-MS) and X-ray photoelectron spectroscopy (XPS). A maximum of ca. 6.3% of Ti surface atoms were found to be solubilized after 24 h of incubation, releasing Ti-ent complexes in the micromolar range that could then be taken up by bacteria in an iron-depleted medium. From a health and environmental point of view, the effects associated to the solubilization of the E171 TiO₂ food additive in the presence of enterobactin and the entrance of the Ti-enterobactin complex in bacteria were questioned.

SUBMITTER: Laisney J

PROVIDER: S-EPMC9599204 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Ligand-Promoted Surface Solubilization of TiO2 Nanoparticles by the Enterobactin Siderophore in Biological Medium.

Laisney Jérôme J Chevallet Mireille M Fauquant Caroline C Sageot Camille C Moreau Yohann Y Predoi Daniela D Herlin-Boime Nathalie N Lebrun Colette C Michaud-Soret Isabelle I

Biomolecules 20221019 10

Titanium dioxide nanoparticles (TiO2-NPs) are increasingly used in consumer products for their particular properties. Even though TiO2 is considered chemically stable and insoluble, studying their behavior in biological environments is of great importance to figure their potential dissolution and transformation. The interaction between TiO2-NPs with different sizes and crystallographic forms (anatase and rutile) and the strong chelating enterobactin (ent) ...[more]

PMID: 36291725

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Dataset Information

Ligand-Promoted Surface Solubilization of TiO₂ Nanoparticles by the Enterobactin Siderophore in Biological Medium.

Publications

Ligand-Promoted Surface Solubilization of TiO<sub>2</sub> Nanoparticles by the Enterobactin Siderophore in Biological Medium.

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