Spectral Properties Echoing the Tautomerism of Milrinone and Its Application to Fe³⁺ Ion Sensing and Protein Staining.

ABSTRACT: Knowledge on the spectral properties of the tautomers of milrinone (MLR) in solvents and solid-state, as well as under light conditions is of critical importance from both theoretical and practical points of view. Herein, we investigated the spectral properties of MLR in different conditions using UV-Vis and fluorescence spectroscopies. The experimental results demonstrated that MLR can undergo the tautomerization reaction induced by solvent polarity, light and pH, eliciting four tautomeric structures (enol, keto, anion, and cation forms). The interesting multi-functional groups in MLR enable it to coordinate with metal ions or to recognize gust molecules by H-bonding. In the use of MLR as an excited-state intermolecular proton transfer (inter-ESPT) fluorescent probe, a highly sensitive an

SUBMITTER: Zhu H 

PROVIDER: S-EPMC9599543 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature