Sleep Disturbance Affects Immune Factors in Clinical Liver Cancer Patients.

ABSTRACT:

Background

Sleep-wake disturbance is prevalent in patients with liver cancer, but there is no direct evidence of its association and related biological mechanisms. Our study was to assess quality of sleep and to describe prevalence of sleep disturbances in patients with different etiologies of liver cancer, especially to explore whether sleep quality influences immune factors.

Methods

A total of 210 patients with liver cancer from August 2015 to December 2015 were randomly divided into two groups including HBV cirrhosis and non-HBV cirrhosis. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate their sleep quality, and then 202 patients enrolled in this study were divided into two groups according to their PSQI scores: PSQI ≤ 5 and PSQI > 5. The association betw

SUBMITTER: Wang Z 

PROVIDER: S-EPMC9600048 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature