Controlling Nutritional Status (CONUT) Score and Sarcopenia as Mutually Independent Prognostic Biomarkers in Advanced Urothelial Carcinoma.

ABSTRACT:

Background

While the controlling nutritional status (CONUT) score and sarcopenia are objective indices of different aspects of a patient's general condition, few studies have comprehensively examined their mutual relationship in patients with advanced cancer.

Methods

This retrospective study included 200 Japanese patients with advanced urothelial carcinoma (aUC). Sarcopenia was diagnosed using Prado's definition. The CONUT score and sarcopenia were examined for their possible association, and their prognostic value was analyzed.

Results

The CONUT score and sarcopenia were not significantly associated. While sarcopenia occurred in 168 patients (84%), more than half of them had normal or only slightly impaired nutritional status, as indicated by a CONUT score of 0-2. Du

SUBMITTER: Une M 

PROVIDER: S-EPMC9600715 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature