Intake of residuals from Atlantic cod attenuated blood pressure increase but did not delay development of kidney damage in obese Zucker fa/fa rats.

ABSTRACT:

Background

Documentation of health effects of residuals after fish filleting may motivate both consumers and producers to increase the use of this under-utilised protein source.

Objectives

The primary objective of the present study was to investigate the effects of a diet containing residuals from Atlantic cod (Gadus morhua) filleting on the development of high blood pressure in obese Zucker fa/fa rats, which spontaneously develop hypertension and proteinuria. The secondary objectives were to investigate any changes in kidney morphology, kidney function and organ damage, and to determine the potential inhibition of cod residuals on renin and angiotensin-converting enzyme (ACE) activities in vitro.

Methods

Male rats were fed diets containing protein powder prepa

SUBMITTER: Vildmyren I 

PROVIDER: S-EPMC9602205 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature