Alterations in the Gut Microbiota and Metabolomics of Seafarers after a Six-Month Sea Voyage.

ABSTRACT: Maintaining the health of seafarers is a difficult task during long-term voyages. Little is known about the corresponding changes in the gut microbiome-host interaction. This study recruited 30 seafarers undertaking a 6-month voyage and analyzed their gut microbiota using 16S rRNA gene sequencing. Fecal untargeted metabolomics analysis was performed using liquid chromatography-mass spectrometry. Significant changes in the composition of the gut microbiota and an increased ratio of Firmicutes/Bacteroidetes at the end (day 180) of the 6-month voyage, relative to the start (day 0), were observed. At the genus level, the abundances of Holdemanella and Plesiomonas were significantly increased, while the abundance of Bacteroides was decreased. Predicted microbi

SUBMITTER: Jiang CH 

PROVIDER: S-EPMC9603232 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature