Longitudinal Serological Surveillance for COVID-19 Antibodies after Infection and Vaccination.

ABSTRACT: The impact of COVID-19 is still felt around the world, and more information is needed regarding infection risk, vaccination responses, and the timing of booster vaccinations. We aimed to evaluate the association of vaccination with closely followed, longitudinal antibody titers and COVID-19 infection events. We conducted a natural history study in a convenience cohort in an ambulatory research unit. We measured anti-nucleocapsid and anti-spike antibody levels every 3 months for 1 year and captured weekly reports of medically confirmed COVID-19 infections. We analyzed the association of antibody titers with infection events as well as the association of the decision to receive vaccination with social, medical, and behavioral characteristics. 629 subjects were followed for 1 year, and 82.8%

SUBMITTER: McGee C 

PROVIDER: S-EPMC9603261 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature