Computational Docking Reveals Co-Evolution of C4 Carbon Delivery Enzymes in Diverse Plants.

ABSTRACT: Proteins are modular functionalities regulating multiple cellular activities in prokaryotes and eukaryotes. As a consequence of higher plants adapting to arid and thermal conditions, C4 photosynthesis is the carbon fixation process involving multi-enzymes working in a coordinated fashion. However, how these enzymes interact with each other and whether they co-evolve in parallel to maintain interactions in different plants remain elusive to date. Here, we report our findings on the global protein co-evolution relationship and local dynamics of co-varying site shifts in key C4 photosynthetic enzymes. We found that in most of the selected key C4 photosynthetic enzymes, global pairwise co-evolution events exist to form functional couplings. Besides, protein-protein interactions between these e

SUBMITTER: Wu C 

PROVIDER: S-EPMC9604239 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature