New Biomarkers and Their Potential Role in Heart Failure Treatment Optimisation-An African Perspective.

ABSTRACT: Heart failure is a clinical syndrome resulting from various cardiovascular diseases of different aetiologies and pathophysiology. These varying pathologies involve several complex mechanisms that lead to the activation of the neurohumoral system, inflammation, angiogenesis, apoptosis, fibrosis, and eventually adverse cardiac remodelling associated with a progressive decline in cardiac function. Once a diagnosis is made, the cardiac function has a gradual decline characterised by multiple hospital admissions. It is therefore imperative to identify patients at different stages of the heart failure continuum to better risk stratify and initiate optimal management strategies. Biomarkers may play a role in the diagnosis, prognostication, and monitoring response to treatment. This review discuss

SUBMITTER: Badianyama M 

PROVIDER: S-EPMC9604249 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature