Nationwide tuberculosis outbreak in the USA linked to a bone graft product: an outbreak report.

ABSTRACT:

Background

Mycobacterium tuberculosis transmission through solid organ transplantation has been well described, but transmission through transplanted tissues is rare. We investigated a tuberculosis outbreak in the USA linked to a bone graft product containing live cells derived from a single deceased donor.

Methods

In this outbreak report, we describe the management and severity of the outbreak and identify opportunities to improve tissue transplant safety in the USA. During early June, 2021, the US Centers for Disease Control and Prevention (CDC) worked with state and local health departments and health-care facilities to locate and sequester unused units from the recalled lot and notify, evaluate, and treat all identified product recipients. Investigators from CDC and the

SUBMITTER: Schwartz NG 

PROVIDER: S-EPMC9605268 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature