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Oral Anticoagulant Discontinuation and Its Predictors in Patients with Atrial Fibrillation.


ABSTRACT:

Background

Oral anticoagulants (OACs) are important in reducing the risk of ischaemic stroke in people with atrial fibrillation (AF). Although patients need to take their OAC continuously, it has been suggested that discontinuation is common in clinical practice, and this could predispose patients to thrombotic complications.

Aims

To investigate the rate of OAC discontinuation and its predictors in patients with AF, using national data from Australian general practices.

Methods

We analysed data obtained from NPS MedicineWise's MedicineInsight dataset. We included patients with a recorded diagnosis of AF who newly started an OAC between 1 January 2013 and 31 December 2017. Patients were considered persistent if an OAC was prescribed continuously without discontinuing m

SUBMITTER: Kefale AT 

PROVIDER: S-EPMC9605276 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature