Peptaibol Production and Characterization from Trichoderma asperellum and Their Action as Biofungicide.

ABSTRACT: Peptaibols (P_aib), are a class of biologically active peptides isolated from soil, fungi and molds, which have interesting properties as antimicrobial agents. P_aib production was optimized in flasks by adding sucrose as a carbon source, 2-aminoisobutyric acid (Aib) as an additive amino acid, and F. oxysporum cell debris as an elicitor. P_aib were purified, sequenced and identified by High-performance liquid chromatography (HPLC)coupled to mass spectrometry. Afterward, a P_aib extract was obtained from the optimized fermentations. The biological activity of these extracts was evaluated using in vitro and in vivo methods. The extract inhibited the growth of specific plant pathogens, and it showed inhibition rates similar to those from commerci

SUBMITTER: Alfaro-Vargas P 

PROVIDER: S-EPMC9605287 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature