Five-Year Cardiovascular Outcomes after Infective Endocarditis in Patients with versus without Drug Use History.

ABSTRACT:

Background

Disparities in treatment and outcomes of infective endocarditis (IE) between people who use drugs (PWUD) and non-PWUD have been reported, but long-term data on cardiovascular and cerebrovascular outcomes are limited. We aim to compare 5-year rates of mortality, cardiovascular and cerebrovascular events after IE between PWUD and non-PWUD.

Methods

Using data from the TriNetX Research Network, we examined 5-year cumulative incidence of mortality, myocardial infarction, heart failure, atrial fibrillation/flutter, ventricular tachyarrhythmias, ischemic stroke, and intracranial hemorrhage in 7132 PWUD and 7132 propensity score-matched non-PWUD patients after a first episode of IE. We used the Kaplan-Meier estimate for incidence and Cox proportional hazards models to est

SUBMITTER: Muncan B 

PROVIDER: S-EPMC9605539 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature