Intercellular interaction mechanisms promote diversity in intracellular ATP concentration in Escherichia coli populations.

ABSTRACT: In fluctuating environments, many microorganisms acquire phenotypic heterogeneity as a survival tactic to increase the likelihood of survival of the overall population. One example of this interindividual heterogeneity is the diversity of ATP concentration among members of Escherichia coli populations under glucose deprivation. Despite the importance of such environmentally driven phenotypic heterogeneity, how the differences in intracellular ATP concentration emerge among individual E. coli organisms is unknown. In this study, we focused on the mechanism through which individual E. coli achieve high intracellular ATP concentrations. First, we measured the ATP retained by E. coli over time when cultured at low (0.1 mM) and control (22.2 mM) concentrations of glucose and obtained the chrono

SUBMITTER: Nakatani RJ 

PROVIDER: S-EPMC9605964 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature