Copper adorned magnetic nanoparticles as a heterogeneous catalyst for Sonogashira coupling reaction in aqueous media.

ABSTRACT: A nanomagnetic hydrophilic heterogeneous copper catalyst, termed γ-Fe₂O₃@PEG@PAMAM G₀-Cu, has been successfully prepared and characterized using FT-IR, XRD, FE-SEM, TEM, EDX, mapping, TGA/DTG, VSM and ICP analyses. The catalyst displayed excellent activity for the palladium-free Sonogashira cross coupling reaction of various aryl iodides and bromides with phenylacetylene derivatives in pure water. The presence of polyethylene glycol coupled with hydrophilic character of the Cu-catalyst adorned on γ-Fe₂O₃ MNPs provides the ready dispersion of the catalyst particles in water, leading to higher catalytic performance as well as facile catalyst recovery via simple magnetic decantation. The recovered catalyst was reused for at least six succ

SUBMITTER: Sheikh S 

PROVIDER: S-EPMC9606120 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature