Pan-cancer analysis reveals the relationship between RCSD1 immune infiltration and clinical prognosis in human tumors.

ABSTRACT:

Background

RCSD1 is a cytoskeletal regulator that has been confirmed to undergo genetic mutations in hematological tumors, but the mechanisms of RCSD1 in pan-cancer and its impact on patient prognosis have not been studied.

Methods

Using TCGA, GEPIA, UALCAN, Kaplan-Meier plotters, Linkedomics, String, cBioPortal, TISIDB, TCIA and TIMER database methods, we investigated the expression of RCSD1 in human tumors and its relationship to clinical prognosis, functional analysis of co-expression networks, mutation status, and immune infiltration in cancers, especially lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC).

Results

The expression of RCSD1 is low in most tumors compared with normal tissues, and its high expression is associated with good patient sur

SUBMITTER: Qiao H 

PROVIDER: S-EPMC9606721 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature