Healthcare-Associated COVID-19 across Five Pandemic Waves: Prediction Models and Genomic Analyses.

ABSTRACT:

Background

Healthcare-associated SARS-CoV-2 infections need to be explored further. Our study is an analysis of hospital-acquired infections (HAIs) and ambulatory healthcare workers (aHCWs) with SARS-CoV-2 across the pandemic in a Belgian university hospital.

Methods

We compared HAIs with community-associated infections (CAIs) to identify the factors associated with having an HAI. We then performed a genomic cluster analysis of HAIs and aHCWs. We used this alongside the European Centre for Disease Control (ECDC) case source classifications of an HAI.

Results

Between March 2020 and March 2022, 269 patients had an HAI. A lower BMI, a worse frailty index, lower C-reactive protein (CRP), and a higher thrombocyte count as well as death and length of stay were significantly

SUBMITTER: Demuyser T 

PROVIDER: S-EPMC9607632 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature