Oxygen-Sensitive Photo- and Radioluminescent Polyurethane Nanoparticles Modified with Octahedral Iodide Tungsten Clusters.

ABSTRACT: The development of cancer treatment techniques able to cure tumors located deep in the body is an urgent task for scientists and physicians. One of the most promising methods is X-ray-induced photodynamic therapy (X-PDT), since X-rays have unlimited penetration through tissues. In this work, octahedral iodide tungsten clusters, combining the properties of a scintillator and photosensitizer, are considered as a key component of nanosized polyurethane (pU) particles in the production of materials promising for X-PDT. Cluster-containing pU nanoparticles obtained here demonstrate bright photo- and X-ray-induced emission in both solid and water dispersion, great efficiency in the generation of singlet oxygen, and high sensitivity regarding photoluminescence intensity in relation to oxygen conce

SUBMITTER: Bardin VA 

PROVIDER: S-EPMC9608458 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature