Protocol for a systematic review and meta-analysis of minimal important differences for generic multiattribute utility instruments.

ABSTRACT:

Introduction

Generic multiattribute utility instruments (MAUIs) are efficient tools for determining and enumerating health-related quality of life. MAUIs accomplish this by generating health state utilities (HSUs) via algorithms. Minimal important differences (MIDs) assist with the interpretation of HSUs by estimating minimum changes that are clinically significant. The overall goal of the proposed systematic review and meta-analysis is the development of comprehensive guidelines for MID estimation.

Methods and analysis

This protocol defines a systematic review and meta-analysis of MIDs for generic MAUIs. The proposed research will involve a comprehensive investigation of 10 databases (EconLit, IDEAs database, INAHTA database, Medline, PsycINFO, Embase, Emcare, JBIEBP and CI

SUBMITTER: Henson GJ 

PROVIDER: S-EPMC9608522 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature