Association between rheumatoid arthritis and thyroid dysfunction: A meta-analysis and systematic review.

ABSTRACT:

Objective

Rheumatoid arthritis (RA) is an autoimmune disorder. Multiple studies have investigated the risk of thyroid dysfunction in patients with RA but have reached conflicting conclusions. This systematic review aimed to determine whether patients with RA are at higher risk of thyroid dysfunction.

Methods

We comprehensively reviewed online literature databases, including PubMed, Scopus, Embase, and the Cochrane Library, from their respective inception dates to March 25, 2022. Studies that provided data on at least one case of thyroid dysfunction in RA patients and their controls were included. Based on these data, we calculated pooled odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) for thyroid dysfunction in RA and non-RA patients.

Results

SUBMITTER: Liu YJ 

PROVIDER: S-EPMC9608862 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature