Prescription characteristics associated with fall-related injury risk among older adults prescribed benzodiazepines: a cohort study.

ABSTRACT:

Background

Benzodiazepines (BZD) are widely prescribed to older adults despite their association with increased fall injury. Our aim is to better characterize risk-elevating factors among those prescribed BZD.

Methods

A retrospective cohort study using a 20% sample of Medicare beneficiaries with Part D prescription drug coverage. Patients with a BZD prescription ("index") between 1 April 2016 and 31 December 2017 contributed to incident (n=379,273) and continuing (n=509,634) cohorts based on prescriptions during a 6-month pre-index baseline. Exposures were index BZD average daily dose and days prescribed; baseline BZD medication possession ratio (MPR) (for the continuing cohort); and co-prescribed central nervous system-active medications. Outcome was a treated fall-related

SUBMITTER: Maust DT 

PROVIDER: S-EPMC9609287 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature