Clinical Trial Quality Assessment in Adult Spinal Surgery: What Do Publication Status, Funding Source, and Result Reporting Tell Us?

ABSTRACT:

Study design

Narrative Review.

Objectives

The objective of this study was to compare publication status of clinical trials in adult spine surgery registered on ClinicalTrials.gov by funding source as well as to identify other trends in clinical trials in adult spine surgery.

Methods

All prospective, comparative, therapeutic (intervention-based) trials of adult spinal disease that were registered on ClinicalTrials.gov with a start date of January 1, 2000 and completion date before December 17, 2018 were included. Primary outcome was publication status of published or unpublished. A bivariate analysis was used to compare publication status to funding source of industry vs non-industry.

Results

Our search identified 107 clinical trials. The most common source of f

SUBMITTER: Danford NC 

PROVIDER: S-EPMC9609521 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature