Prevention and Eradication of Biofilm by Dendrimers: A Possibility Still Little Explored.

ABSTRACT: Multidrug resistance (MDR) among pathogens and the associated infections represent an escalating global public health problem that translates into raised mortality and healthcare costs. MDR bacteria, with both intrinsic abilities to resist antibiotics treatments and capabilities to transmit genetic material coding for further resistance to other bacteria, dramatically decrease the number of available effective antibiotics, especially in nosocomial environments. Moreover, the capability of several bacterial species to form biofilms (BFs) is an added alarming mechanism through which resistance develops. BF, made of bacterial communities organized and incorporated into an extracellular polymeric matrix, self-produced by bacteria, provides protection from the antibiotics' action, resulting in

SUBMITTER: Alfei S 

PROVIDER: S-EPMC9610720 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature