Haemophilus influenzae Carriage among Healthy Children in Portugal, 2015-2019.

ABSTRACT: Haemophilus influenzae is an important cause of mucosal and invasive infections and a common colonizer of the upper respiratory tract. As there are no recent data on H. influenzae carriage in Portugal, we aimed to characterize carriage samples and investigate possible parallelisms with disease isolates. Between 2016-2019, 1524 nasopharyngeal samples were obtained from children (0-6 years) attending day-care. H. influenzae were serotyped and screened for β-lactamase production. Strains producing β-lactamase and/or those that were encapsulated were further characterized by antibiotype; encapsulated strains were also investigated for MLST and the presence of antimicrobial resistance and virulence genes (extracted from whole genome sequencing). The overall carriage rate wa

SUBMITTER: Bajanca-Lavado MP 

PROVIDER: S-EPMC9611606 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature