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Thromboembolic Disease and Cardiac Thrombotic Complication in COVID-19: A Systematic Review.


ABSTRACT: The coronavirus 2019 pandemic has affected many healthcare systems worldwide. While acute respiratory distress syndrome (ARDS) has been well-documented in COVID-19, there are several cardiovascular complications, such as myocardial infarction, ischaemic stroke, and pulmonary embolism, leading to disability and death. The link between COVID-19 and increasing thrombogenicity potentially occurs due to numerous different metabolic mechanisms, ranging from endothelial damage for direct virus infection, associated excessive formation of neutrophil extracellular traps (NETs), pathogenic activation of the renin-angiotensin-aldosterone system (RAAS), direct myocardial injury, and ischemia induced by respiratory failure, all of which have measurable biomarkers. A search was performed by interrogatin

SUBMITTER: Nappi F 

PROVIDER: S-EPMC9611930 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature