Uric Acid Levels Are Associated with Bone Mineral Density in Mexican Populations: A Longitudinal Study.

ABSTRACT:

Background

Inconsistent epidemiological evidence between uric acid (UA) and bone mineral density (BMD) has been observed. Therefore, we evaluated the association between UA and BMD in Mexican adults.

Methods

This analysis was conducted on 1423 participants from the Health Workers Cohort Study. We explored cross-sectional associations using linear regression and longitudinal associations using fixed-effects linear regression by sex and age groups (<45 and ≥45 years).

Results

In females <45 years old, the cross-sectional analysis showed that UA levels were positively associated with total hip BMD. However, in the longitudinal analysis, we observed a negative association with the femoral neck and lumbar spine BMD. In contrast, in males <45 years old, we found an

SUBMITTER: Robles-Rivera K 

PROVIDER: S-EPMC9612067 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature