Community structured model for vaccine strategies to control COVID19 spread: A mathematical study.

ABSTRACT: Initial efforts to mitigate the COVID-19 pandemic have relied heavily on non-pharmaceutical interventions (NPIs), including physical distancing, hand hygiene, and mask-wearing. However, an effective vaccine is essential to containing the spread of the virus. We developed a compartmental model to examine different vaccine strategies for controlling the spread of COVID-19. Our framework accounts for testing rates, test-turnaround times, and vaccination waning immunity. Using reported case data from the city of Toronto, Canada between Mar-Dec, 2020 we defined epidemic phases of infection using contact rates as well as the probability of transmission upon contact. We investigated the impact of vaccine distribution by comparing different permutations of waning immunity, vaccine coverage and eff

SUBMITTER: Aruffo E 

PROVIDER: S-EPMC9612529 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature