Resting state connectivity predictors of symptom change during gaze-contingent music reward therapy of social anxiety disorder.

ABSTRACT:

Background

Social anxiety disorder (SAD) is common, first-line treatments are often only partially effective, and reliable predictors of treatment response are lacking. Here, we assessed resting state functional connectivity (rsFC) at pre-treatment and during early treatment as a potential predictor of response to a novel attention bias modification procedure, gaze-contingent music reward therapy (GC-MRT).

Methods

Thirty-two adults with SAD were treated with GC-MRT. rsFC was assessed with multi-voxel pattern analysis of fMRI at pre-treatment and after 2-3 weeks. For comparison, 20 healthy control (HC) participants without treatment were assessed twice for rsFC over the same time period. All SAD participants underwent clinical evaluation at pre-treatment, early-treatment (wee

SUBMITTER: Zhu X 

PROVIDER: S-EPMC9612546 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature