Non-invasive characterization of pleural and pericardial effusions using T1 mapping by magnetic resonance imaging.

ABSTRACT:

Aims

Differentiating exudative from transudative effusions is clinically important and is currently performed via biochemical analysis of invasively obtained samples using Light's criteria. Diagnostic performance is however limited. Biochemical composition can be measured with T1 mapping using cardiovascular magnetic resonance (CMR) and hence may offer diagnostic utility for assessment of effusions.

Methods and results

A phantom consisting of serially diluted human albumin solutions (25-200 g/L) was constructed and scanned at 1.5 T to derive the relationship between fluid T1 values and fluid albumin concentration. Native T1 values of pleural and pericardial effusions from 86 patients undergoing clinical CMR studies retrospectively analysed at four tertiary centres. Effusions

SUBMITTER: Rosmini S 

PROVIDER: S-EPMC9612798 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature