Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics.

ABSTRACT: With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the first documented pandemic due to a coronavirus that continues to be a major health challenge. Despite being rapid, uncontrollable, and highly infectious in its spread, it also created incentives for technology development and redefined public health needs and research agendas to fast-track innovations to be translated. Breakthroughs in computational biology peaked during the pandemic with renewed attention to making all cutting-edge technology deliver agents to combat the disease. The demand to develop effective treatments yielded surprising collaborations from previously segregated fields of science and technology. The long-standing pharmaceutical industry's aversion to repurposing existing drugs

SUBMITTER: Gupta Y 

PROVIDER: S-EPMC9613808 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature